Sara Ramirez – Callie Torres Then

Callie began as a recurring character on Grey's Anatomy and became a regular. She married George, but they split after his affair with Izzie. Callie then discovered she was bisexual and had a brief relationship with Erica Hahn.

She married Arizona Robbins, but their marriage faced challenges after Callie got pregnant with Mark Sloan's child. Following a plane crash, Callie approved Arizona's leg amputation, which led to their marriage's downfall.

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