What's going on here?
In "Avengers: Endgame," there is a significant moment when Captain America is deemed worthy to wield Thor's enchanted hammer, Mjolnir. This moment is a culmination of various elements from Norse mythology, where only those deemed worthy can lift Mjolnir and gain Thor's powers.
The meme humorously imagines how Thanos, who likely has no prior knowledge of Norse mythology or the significance of Mjolnir, would react to this situation. It uses the popular "confused Pikachu" meme format to humorously depict Thanos' bewilderment while the rest of us had surprised expressions when witnessing the scene in the movie.