Warren Beatty and Annette Bening (21-Year Age Difference)

A 21-year age difference hasn't escaped notice in the relationship of Warren Beatty and Annette Bening. Their enduring bond, established through marriage in 1992, has frequently spurred discussions about their age gap.

Addressing this topic, Beatty once noted, "Everybody who has an age difference in their marriage has to address it at times because you're at different stages in your life. You're going through different things. You must have a fundamental love and mutual respect for one another for it to work."

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